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From Karnataka Open Educational Resources
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, 12:00, 6 April 2018
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− | Francis Crick and Thomas Watson - physicist and ornithologist - made one of the most important discoveries of molecular biology in the last century. They discovered the structure of the deoxyribonucleic acid (DNA) the repository of genetic material.
| + | A question in a Physics exam at the University of Copenhagen, Denmark several decades ago said: "Describe how to determine the height of a skyscraper with a barometer." One student replied: "You tie a long piece of string to the neck of the barometer, then lower the barometer from the roof of the skyscraper to the ground. The length of the string plus the length of the barometer will equal the height of the building." |
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− | While the structure of the constituents itself was known, it took several scientists to discover the framework. While Watson and Crick were awarded the Nobel Prize for proposing the double helix model of the DNA - described by molecular biologists as sublimely beautiful, another biophysicist Rosalind Franklin made several crucial discoveries of the DNA including one of the forms of the double helix. Her X-ray crystallography images provided the crucial links and inputs for formulation of a helical model. Rosalind Franklin died before the announcement of the Nobel Prize and her contribution to the discovery of the DNA remained known only to molecular biologists and geneticists.
| + | This highly original answer so incensed the examiner that the student was failed. The student appealed on the grounds that |
| + | his answer was indisputably correct, and the university appointed an independent arbitrator to decide the case. |
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− | More information can be found [http://www.nobelprize.org/nobel_prizes/medicine/laureates/1962/crick-bio.html here]
| + | The arbitrator judged that the answer was indeed correct, but did not display any noticeable knowledge of physics. To resolve the problem it was decided to call the student in and allow him six minutes in which to show a minimal familiarity with the basic principles of Physics. |
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| + | For five minutes the student sat in silence, forehead creased in thought. The arbiter reminded him that time was running out, to which the student replied that he had several extremely relevant answers, but couldn't make up his mind which to use. On being advised to hurry up the student replied as follows: "Firstly, you could take the barometer up to the roof of the skyscraper, drop it over the edge, and measure the time it takes to reach the ground. The height of the building can then be worked out from the formula H = 0.5g x t squared. But bad luck on the barometer." |
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− | Image:resized-photo-of-dna-model.jpeg
| + | "Or if the sun is shining you could measure the height of the barometer, then set it on end and measure the length of its shadow. Then you measure the length of the skyscraper's shadow, and thereafter it is a simple matter of proportional arithmetic to work out the height of the skyscraper." |
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| + | "But if you wanted to be highly scientific about it, you could tie a short piece of string to the barometer and swing it like a pendulum, first at ground level and then on the roof of the skyscraper. The height is worked out by the difference in the gravitational restoring force T = 2 pi square root (l / g)." |
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| + | "Or if the skyscraper has an outside emergency staircase, it would be easier to walk up it and mark off the height of the skyscraper in barometer lengths, then add them up." |
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| + | "If you merely wanted to be boring and orthodox about it, of course, you could use the barometer to measure the air pressure on the roof of the skyscraper and on the ground, and convert the difference in millibars into feet give the height of the building." |
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| + | "But since we are constantly being exhorted to exercise independence of mind and apply scientific methods, undoubtedly the best way would be to knock on the janitor's door and say to him 'If you would like a nice new barometer, I will give you this one if you tell me the height of this skyscraper'." |
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| + | The student was Niels Bohr, who went on to win the Nobel Prize for Physics. |
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| + | For more stories about scientists click [[Famous_Scientists|here]] |